The related field of epigenetics aims to elucidate the role of specific epigenetic elements in biological processes, such as DNA methylation changes in diseases including cancer.Īgena BIOSCIENCE's MassARRAY® System is a powerful tool for downstream marker validation and large-scale agricultural research. Often referred to as “personalized medicine,” it is based on ascertaining the relevant variance of individuals versus average responses of whole populations. The relationship between a person’s genetic makeup and the way that person responds to and metabolizes drugs - plays an important role in healthcare today. Genomic biomarkers with potential clinical utility may be associated with disease state or therapeutic response, and include SNPs, somatic mutations, expressed RNA transcripts, DNA methylation regions, and copy number variations. Mutations play a key role as biomarkers for risk, progression, and prognosis. Genetic and somatic mutations can be employed to study their effect on oncogenesis, disease progression, or therapeutic response.
Complex diseases, including cancer, cardiovascular disease, and neurological disorders, are often associated with multiple genetic and epigenetic factors, requiring flexible and customizable analysis tools. Identifying and studying genetic factors that contribute to disease requires sophisticated research tools and complex experimental designs. Highly accurate, sensitive analysis for cancer research.Pathogen identification/molecular typing.
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Agena BIOSCIENCE offers Genotyping, Somatic mutation profiling, Methylation analysis, Quantitative gene expression, Pathogen identification/molecular typing and clinical molecular genetics testing, such as MaterniT21 PLUS, a noninvasive prenatal test for trisomy 21, trisomy 18, and trisomy 13, RetnaGene AMD a genetic test for risk of progression for age-related macular degeneration, Heredi-T Cystic Fibrosis Screening Test, and the SensiGene Fetal RHD Genotyping Test.Īgena BIOSCIENCE provides best-in-class laboratory testing services with a focus on prenatal and ophthalmological diseases and conditions, including the market-leading MaterniT21™ PLUS noninvasive prenatal laboratory-developed test intended for use in pregnant women at increased risk for fetal aneuploidies. Agena BIOSCIENCE's proprietary MassARRAY® System is a high-performance MALDI-TOF mass spectrometry-based DNA analysis platform that delivers reliable and specific data from biological samples and from genetic target material that is only available in trace amounts.Īgena BIOSCIENCE is a manufacturer of DNA massarrays platform and is used for SNP genotyping, methylation detection and quantitative gene expression analysis.
Agena BIOSCIENCE provides technologies and tools for translational research, oncology, agricultural genomics and clinical diagnostics.
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